Stéatose au cours de l’hépatite chronique C : Prévalence et facteurs de risque de survenue
Mots-clés :
Hépatite chronique C, stéatoseRésumé
Prérequis : La stéatose semble fréquente chez les patients infectés par le virus de l'hépatite C. Les facteurs prédictifs de survenue d’une stéatose au cours des hépatites chroniques C ont été à l’origine de nombreux travaux récents.But : Déterminer la prévalence de la stéatose au cours de l’hépatite chronique C et rechercher les facteurs de risque associés à la stéatose.
Méthodes : Nous avons réalisé une étude prospective, incluant 50 patients suivis pour une hépatite chronique C. Les malades ont été subdivisés en 2 groupes selon la présence ou non de stéatose et comparés.
Résultats : La prévalence de la stéatose était de 56%. En analyse multivariée, l’âge et l’hypertriglycéridémie étaient des facteurs prédictifs indépendants. L’Odds ratio pour un âge supérieur à 58 ans était de 2 et pour un taux de triglycérides supérieur à 1,1 μmol/l de 4,22.
Conclusion : Dans cette étude, la stéatose était associée uniquement aux facteurs métaboliques.
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