Une séquence Siemens de cartographie T1 en acquisition single-shot comme alternative à MOLLI
DOI :
https://doi.org/10.62438/tunismed.v104i05.6107Mots-clés :
IRM cardiaque, cartographie T1, Single-Shot, alternative à MOLLI, caractérisation myocardiqueRésumé
Contexte : La cartographie T1 native constitue aujourd’hui un outil essentiel pour la caractérisation quantitative du tissu myocardique en imagerie par résonance magnétique cardiaque (IRM cardiaque). Toutefois, les techniques de référence telles que la séquence Modified Look-Locker Inversion
Recovery (MOLLI) restent limitées par leur nature propriétaire et leur accessibilité restreinte, en particulier dans les contextes à ressources limitées.
Objectif : Cette étude vise à développer et valider une technique de cartographie T1 en acquisition single-shot, plus accessible, comme alternative pratique à MOLLI, et à évaluer ses performances diagnostiques ainsi que son degré d’accord avec une méthode de référence.
Méthodes : Une étude rétrospective a été menée sur 40 sujets (25 volontaires sains et 15 patients présentant des pathologies cardiaques) ayant bénéficié d’une IRM cardiaque à 3T. Les valeurs de T1 natif ont été acquises à l’aide d’un schéma d’inversion Single-Shot modifié (3(3)3(3)5).
L’analyse quantitative a été réalisée via un traitement dédié sous MATLAB et comparée aux mesures issues du logiciel de référence CVI⁴². L’accord entre les méthodes a été évalué par analyse de Bland–Altman, et les comparaisons intergroupes par test t de Student.
Résultats : Les patients atteints de pathologies cardiaques présentaient des valeurs de T1 significativement plus élevées que les sujets sains (1566± 65 ms vs. 1079 ± 80 ms, p < 0,001). La méthode proposée a montré un excellent accord avec la référence, avec une différence moyenne de 5,7 ms sans biais statistiquement significatif. Par ailleurs, l’approche Single-Shot a présenté une variabilité .....( résumé tronqué à 250 mots).
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