Implications thérapeutiques des récentes études sur la stratégie de prise en charge des cancers bronchiques non à petite cellule
Mots-clés :
Cancer broncho pulmonaire, histologie, traitement, évolutionRésumé
Prérequis : Le cancer broncho pulmonaire est un problème de santé publique majeur dont le pronostic est le plus souvent défavorable. Pendant longtemps, les stratégies de prise en charge de ce cancer ont peu pris en considération le type histologique et peu d’auteurs se sont attardés à l’étude de l’implication du type histologique du cancer sur le devenir des malades atteints.But : A la lumière des résultats des récentes études, nous nous proposons de revoir les récents aspects épidémiologiques et biologiques des cancers bronchiques puis d’étudier l’impact sur la stratégie thérapeutique.
Méthodes : Revue de la littérature
Résultats : les avancées scientifiques et la découverte de nouveaux mécanismes de cancérogénèse élargissent considérablement les cibles potentielles thérapeutiques et permettent d’adopter une approche plus spécifique de la cellule cancéreuse.
Conclusion : Malgré les progrès observés en cancérologie thoracique, les bénéfices en terme de survie restent modeste l’avènement de nouvelles molécules ciblant spécifiquement une étape de l’oncogenèse permet une meilleure sélectivité thérapeutique et une toxicité moindre.
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