Fertilité et Maladies Inflammatoires Chroniques de L’intestin
Mots-clés :
Maladies inflammatoires chroniques de l'intestin, maladie de Crohn, rectocolite hémorragique, fertilitéRésumé
Prérequis : Les données de la littérature concernant la fertilité au cours des maladies inflammatoires chroniques de l’intestin sont insuffisantes et parfois contradictoires. Les buts de cette mise au point sont de passer en revue l’impact des MICI ainsi que de leur traitement médical et chirurgical sur la fertilité aussi bien féminine que masculine.
Méthodes : Revue de la littérature.
Résultats : Le risque d’infertilité semble être majoré chez un sous groupe de malades et fait intervenir plusieurs facteurs dont, en particulier pour la maladie de Crohn, l’activité de la maladie et l’impact psychologique induit par cette affection chronique. La diminution de la fertilité, aussi bien féminine que masculine, au cours
de la rectocolite hémorragique est essentiellement liée à la chirurgie.
Les données concernant l’impact des différentes thérapeutiques utilisées au cours des MICI sur la fertilité sont très insuffisantes et intéressent surtout la fertilité masculine.
Téléchargements
Références
Khosla R, Willoughby CP, Jewell DP. Crohn's disease and pregnancy. Gut 1984; 25: 52-56
Larzillière I, Beau P. Maladie inflammatoires chroniques intestinales et grossesse. Gastroenterol Clin Biol 1998; 22: 1056-1060
Cléandre D, Dufour Ph, Tiberghien B, Bernardi C, Vinatier, Monnier JC. Entérocolites chroniques idiopathiques et grossesse. J Gynecol Obstet Biol Reprod 1993; 22: 59-65
Alstead EM. Inflammatory bowel disease in pregnancy. Postgrad Med J 2002; 78: 23-26
Alstead EM, Nelson-Piercy C. Inflammatory bowel disease in pregnancy. Gut 2003; 52: 159-161
Couve S, Seksik P, Elefant E, Jian R, Marteau P. Maladies inflammatoires de l'intestin et procréation. Gastroenterol Clin Biol 2003; 27: 618-626
Karoui S, Boubaker J, Filali A. Maladies inflammatoires cryptogénétiques de l'intestin et grossesse. Revue Tunisienne de la Santé Militaire 2004; 6: 185-90
De Dombal FT, Burton IL, Goligher JC. Crohn's disease and pregnancy. Br Med J 1972; 3: 550-3
Mayberry JF, Weterman IT. European survey of fertility and pregnancy in women with Crohn's disease: a case control study by European Collaborative Group. Gut 1986; 27: 821-825
Hudson M, Flett G, Sinclair TS, Brunt PW, Templeton A, Mowat. NA. Fertility and pregnancy in inflammtory bowel disease. Int J Gynaecol Obstet 1997; 58: 229-37
Baird DD, Narendranathan M, Sandler RS. Increased risk of preterm birth of women with inflammatory bowel disease. Gastroenterology 1990; 99: 987-4
Ording Olsen K, Juul S, Berndtsson I, Oresland T, Laurberg S. Ulcerative colitis: female fecundity before diagnosis, during disease, and after surgery compared with a population sample. Gastroenterology 2002; 122: 15-
Johnson P, Richard C, Ravid A. Female infertility after ileal pouch-anal anastomosis for ulcerative colitis. Dis Colon Rectum 2004; 47: 1119- 26
Willoughby CP, Truelove SC. Ulcerative colitis and pregnancy. Gut 1980; 21: 469-474
Narendranathan M, Sandler RS, Suchindran CM, Savitz DA. Male infertility in inflammatory bowel disease. J Clin Gastroenterol 1989; 1: 403-6
Drollette CM, Badawy SZ. Pathophysiology of pelvic adhesions. Modern trends in preventing infertility. J Reprod Med 1992; 37: 107- 21
Drossman DA, Patrick DL, Mitchell CM, Zagami EA, Appelbaum MI. Health related quality of life in inflammatory bowel disease - functionnal status and patient worries and concerns. Dig Dis Sci 1989; 34: 1379-1386
Colombel JF, Yazdanpanah Y, Laurent F, Houcke P, Delas N, Marquis P. Qualité de vie dans les maladies inflammatoires chroniques de l'intestin. Validation d'un questionnaire et premières données françaises. Gastroenterol Clin Biol 1996; 20: 1071-1077
Dozois RR, Nelson H, Metcalf AM. Fonction sexuelle après anastomose iléo-anale. Ann Chir 1993 ; 47 : 1009-1013
Godeberge P. Traitement des lésions anopérinéales de la maladie de Crohn. Gastroenterol Clin Biol 2005; 29: 166-177
Andersson P, Olaison G, Bendsten P, Myrelid P, Sjodahl R. Health related quality of life in Crohn's proctocolitis does not differ from a general population when in remission. Colorectal Dis 2003; 5: 56-62
Crohn's disease: ‘its gynaecologic aspect'. Am J Obstet Gynecol 1978; 131: 196-202
O'Morain C, Smethurst P, Doré CJ, Levi AJ. Reversible male infertility due to sulphasalazine: studies in man and rats. Gut 1984; 25: 1078-1084
Hudson E, Dore C, Sowter C, Toovey S, Levi AJ. Sperm size in patients with inflammatory bowel disease on sulfasalazine therapy. Fertil Steril 1982; 38: 77-84
Riley SA, Lecarpentier J, Mani V, Goodman MJ, Mandal BK, Turnberg LA. Sulphasalazine induced seminal abnormalities in ulcerative colitis: results of mesalasine substitution. Gut 1987; 28: 1008-1012
Di Paolo MC, Paoluzi OA, Pica R. sulphasalazine and 5- aminosalicylic acid in long term treatment of ulcerative colitis: report on tolerance and side-effects. Dig Liver Dis 2001; 33: 563-9
Di Paolo MC, Paoluzi OA, Pica R. sulphasalazine and 5- aminosalicylic acid in long term treatment of ulcerative colitis: report on tolerance and side-effects. Dig Liver Dis 2001; 33: 563-9
Pholpramool C, Srikhao A. Antifertility effect of sulfasalazine in the male rat. Contraception 1983; 28: 273-9
Fukushima T, Kato M, Adachi T, Hamada Y, Horimoto M, Komiyama M, Mori C, Horii I. Effects of sulfasalazine on sperm acrosome reaction and gene expression in the male reproductive organs of rats. Toxicol Sci 2005; 85: 675-82
Reimers TJ, Sluss PM. 6-mercaptopurine treatment of pregnant mice: effects on second and third generation. Science 1978; 201: 65-7
Dejaco C, Mittermaier C, Reinisch W, Gasche C, Waldhoer T, Strohmer H, Moser G. Azathioprine treatment and male fertility in inflammatory bowel disease. Gastroenterology 2001; 121: 1048-53
Ligumsky M, Badaan S, Lewis H, Meirow D. Effects of 6- mercaptopurine treatment on sperm production and reproductive performance: a study in male mice. Scand J Gastroenterol 2005; 40: 444-9
Desreumaux P. Immunosuppresseurs et MICI. Gastroenterol Clin Biol 2004; 28: 685-695
Affleck JG, Neumann K, Wong L, Walker VK. The effects of methotrexate on Drosophilia development female fecundity, and gene expression. Toxicol Sci 2006; 89: 495-503
Loyd ME, Carr M, Mcelhtton P, Hall GM, Hughes RA. The effects of methotrexate on pregnancy, fertility and lactation. Q J Med 1999; 92: 551-563
Srinivas M, Agarwala S, Datta Gupta S. Effects of cyclosporine on fertility in male rats. Pediatr Surg Int 1998; 13: 388-91
Seethalakshmi L, Menon M, Malhotra RK, Diamond DA. Effects of cyclosporine Aon male reproduction in rats. J Urol 1987; 138: 991-995
Seethalakshmi L, Menon M, Pallias JD, Khauli RB, Diamond DA. Cyclosporine: its harmful effects on testicular function and male fertility. Transplant Proc 1989; 21: 928-30
Mahadevan U, Terdiman JP, Aron J, Jacobsohn S, Turek P. Infliximab and semen quality in men with inflammatory bowel disease. Inflamm Bowel Dis 2005; 11: 395-9
Tiainen J, Matikainen M, Hiltunen KM. Ieal J-pouch-anal anastomosis, sexual dysfunction and fertility. Scand J Gastroenterol 1999; 34: 185-8
Oresland T, Palmblad S, Ellstrom M, Berndtsson I, Crona N, Hulten L. Gynaecological and sexual function related to anatomical changes in the female pelvis after restorative proctocolectomy. Int J Colorectal Dis 1994; 9: 77-81
Moody GA, Mayberry JF. Perceived sexual dysfunction amongst patients with inflammatory bowel disease. Digestion 1993; 54: 256-60
Sagar PM, Lewis W, Holdsworth PJ, Johnston D, Mitchel C, MacFie J. Quality of life after restorative proctocolectomy with a pelvic ileal reservoir compares favourably with that of patients with medically treated colitis. Dis Colon Rectum 1993; 36: 584-592
Mortier PE, Gambiez L, Karoui M, Cortot A, Paris JC, Quandalle P, Colombel JF. Colectomy with ileorectal anastomosis preserves female fertility in ulcerative colitis. Gastroenterol Clin Biol 2006; 30: 594-597
Berdah SV, Orsoni P, Linzberger N, Frederick J, Picaud R. Coloproctectomie totale avec anastomose iléo anale vidéo assistée. Ann Chir 2001; 126: 445-7
Beaugerie L, Penna C. Rectocolite hémorragique : anastomose iléo rectale ou iléo anale ? Gastroenterol Clin Biol 2000; 24: B39-B46