Survival in patients with gastric lymphoma
Keywords:
Primary gastric lymphoma; survival; prognostic factorsAbstract
Background: Mucosa-associated lymphoid tissue lymphoma is a histological type of marginal zone non-Hodgkin's lymphoma. Its clinical features and prognosis have seldom been reported because of its indolent clinical course.
Aim: To establish prognostic factors that should be considered for the staging and management of this disease.
Methods: Clinical data of 40 pathologically confirmed gastric lymphoma patients, treated during a period of 13 years, were analyzed.
Results: Of the 40 patients, 65% had stage IE - II1E disease and 35% had stage II2E - IV disease. A total of 18 patients received surgeries.Eighteen patients had chemotherapy and 10 patients had Helicobacter Pylori eradication therapy. The complete remission rate after treatment was 50%. The patients were followed up for a median of 26.75 months. The 5-year overall survival rate was 70%. Early stage at presentation, surgery, normal lactic dehydrogenase (LDH) levels and Helicobacter Pylori infection were associated with longer survival in univariate analysis.
Conclusion: This study suggested that surgery might be an important factor predicting the long-term survival of patients with primary gastric lymphoma. Patients with poor prognostic factors should be treated more aggressively.
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