Late Stent Thrombosis In a Young Patient who had Ulcerative Colitis .
Keywords:
Thrombosis, stent, ulcerative colitis, inflammationAbstract
Background : Arterial and venous thrombosis are well recognized systemic complications of inflammatory bowel disease predominantly in patients with crohn’s colitis and in those with ulcerative colitis (UC).
Aim : report a new case
Case : We describe the case of a 35 years old man presenting previously an anterior infarct with a tighten stenosis in the middle part of the left anterior descending artery (LAD). The stenosis was treated percutaneously with a bare stent deployment. During an acute exacerbation of UC, the patient developed an acute coronary
syndrome with ST elevation secondary to a late stent thrombosis, needing a primary coronary angioplasty. Following course is
favorable.
Conclusion : Based on this case, we’ll discuss the relationship between UC and thrombosis, and therapeutic considerations inherent to thrombotic and bleeding risks.
Downloads
References
Talbot RW, Heppel J, Dozois RR et al. Vascular complications of inflammatory bowel disease. Mayo Clin Proc. 1986 ;61 :140-5.
Colombel JF, Desreumaux P, Klein O. Maladies inflammatoires chroniques de l'intestin. Hepato-Gastro 1994; 2:143-55
Cortot A. Maladies inflammatoires chroniques de l'intestin. ATraitement médical. Hepato-Gastro 1994; 6 : 541-50
Vissuzaine C, Danne O, Jouglin J, Soullard J, Mignon M. Les lésions histologiques du rectum restant après anastomose iléorectale pour rectocolite hémorragique. Gastroenterol Clin Biol 1979 ; 3 : 631-6
Efremidis M, Prappa E, Kardaras F. Acute myocardial infarction in a young patient during an exacerbation of ulcerative colitis. Int J Cardiol 1999; 70:211-2.
Mutlu B, Ermeydan M.H , Feruze E et al. Acute myocardial infarction in a young woman with severe ulcerative colitis. International Journal of Cardiology 2002; 83:183 -5
Batty V, Blain H, Saadi L et al. Fatal myocardial infarction in an elderly woman with severe ulcerative colitis : what is the role of steroids? Am J Gastroenterol 1998; 93:2000-1.
Thompson NP, Wakefield AJ, Pounder RE. Inherited disorders of coagulation appear to protect against inflammatory bowel disease. Gastroenterology 1995; 108:1011-5
Gaffney PR, Doyle CT, Gaffney A et al. Paradoxical response to heparin in 10 patients with ulcerative colitis. Am J Gastroenterol 1996; 91:1221-5.