Microcystic serous pancreatic cystadenoma
Keywords:
Pancreas, Cystic neoplasms, Serous cystadenomaAbstract
Background : The pancreatic cystic serous neoplasms are divided into two categories: benign serous cystadenoma (SCA) and malignant serous cystadenocarcinoma. Furthermore, based on the macroscopic appearances, SCAs are subdivided into serous microcystic adenomas (SMAs) and serous oligocystic or macrocystic adenomas.
Aim: Report of a new case of SMA in which we emphasize on the diagnostic difficulties encountered against such tumor despite its relatively radiological easiness compared to the other variants.
Case report: We report the case of 84 year-old-woman with a microcystic serous cystadenoma of the pancreas which was identified on pathologic examination of the surgical specimen, after unconclusive abdominal ultrasound and computed tomography (CT)- scan.
Conclusion: This case describes this rare entity and emphasizes that the diagnosis of such entity is still based on pathological examination after tumor removal.
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Fujiwara H, Ajiki T, Fukuoka K, Mitsutsuji M, Yamamoto M, Kuroda Y. Macrocystic serous cystadenoma of the pancreas. J Hepatobiliary Pancreat Surg 2000; 7: 92-6.
Le Borgne J, de Calan L, Partansky C. Cystadenomas and cystadenocarcinomas of the pancreas: a multiinstitutional retrospective study of 398 cases. Ann Surg 1999; 230: 152-61.
Morohoshi T, Held G, Kloppel G. Exocrine pancreatic tumours and their histological classification. A study based on 167 autopsy and 97 surgical cases. Histopathology 1983; 7: 645-61.
Solcia E, Capella C, Kloppel G. Tumours of the pancreas. AFIP Atlas of Tumor Pathology. 3rd ed. Washington, DC: Armed Forces Institute of Pathology, 1997.
Yamaguchi K, Enjoji M. Cystic neoplasms of the pancreas. Gastroenterology 1987; 92: 1934-43.
Pyke CM, Van heerden JA, Colby TV, Sarr Mg, Weaver AL. The spectrum of serous cystadenoma of the pancreas. Clinical, Pathologic, and surgical aspects. Ann surg 1992; 215: 132-9.
Yamamoto T, Takahashi N, Yamaguchi T, Imamura Y. A case of solid variant type of pancreatic serous cystadenoma mimicking islet cell tumor. Clinical Imaging 2004; 28: 49-51.
Healy JC, Davis SE, Reznek RH. CT of microcystic (serous) pancreatic adenoma. J Comput Assist Tomogr 1994; 18: 146-8.
Sperti C, Pasquali C, Perasole A et al. Macrocystic serous cystadenoma of the pancreas clinicopathologic features in seven cases. Int J Pancreatol 2000; 28: 1-7.
Yamaguchi K, Tanaka M. Radiologic imaging of cystic neoplasms of the pancreas. Pancreatology 2001; 1: 633-6.
Procacci C, Biasutti C, Carbognin G et al. Characterization of cystic tumors of the pancreas: CT accuracy. J Comput Assist Tomogr 1999; 23: 906-12.
Kaneto H, Endo T, Ozeki I, Itoh H, Sasaki S, Mukaiya M. Macrocystic serous cystadenoma of the pancreas: importance of coexistent tiny cysts depicted by EUS. J Gastroenterol 2000; 35: 472- 5.
Hammel P, Bernades P. Les lésions kystiques du pancréas de diagnostic difficile. Presse Médicale 1996; 25: 1794-800.
Palazzo L, Hammel P, Cellier C, Ruszniewski Ph. Les tumeurs kystiques du pancréas. Acta Endoscopica 1999; 29: 418-22.
Kehagias D, Smyrniotis V, Kalovidouris A et al. Cystic tumors of the pancreas preoperative imaging, diagnosis, and treatment. Int Surg 2002; 87: 171-4.
Brugge WR. Role of endoscopic ultrasound in the diagnosis of cystic lesions of the pancreas. Pancreatology 2001; 1: 637-40.
Procacci C, Graziani R, Bicego E et al. Serous cystadenoma of the pancreas report of 30 cases with emphasis on the imaging findings. J Comput Assist Tomogr 1997; 21: 373-82.
Torresan F, Casadei R, Solmi L et al. The role of ultrasound in the differential diagnosis of serous and mucinous cystic tumors of the pancreas. Eur J Gastroenterol Hepatol 1997; 9: 169-72.
Bassi C, Salvia R, Molinari E, Biasutti C, Falconi M, Pederzoli P. Management of 100 consecutive cases of pancreatic serous cystadenoma: wait for symptoms and see at imaging or vice versa? World J Surg 2003; 27: 319-23.
Capella C, Solcia E, Klöppel G, Hruban RH. Serous cystic neoplasms of the pancreas. In; Hamilton SR, Aaltonen LA, eds. World Health Organization Classification of Tumors. Pathology and genetics of Digestive System. Lyon: IARC Press, 2000: 231-2.
Alpert LC, Truong LD, Bossart MI, Spjut HJ. Microcystic adenoma (serous cystadenoma) of the pancreas. A study of 14 cases with immunohistochemical, and electron-microscopic correlation. Am J Surg Pathol 1988; 12: 251-63.
Egawa N, Maillet B, Schroder S, Mukai K, Klöppel G. Serous oligocystic and ill-demarcated adenoma of the pancreas: a variant of serous cystic adenoma. Virchows Arch 1994; 424: 13-7.
Ishikawa T, Nakao A, Nomoto S et al. Immunohistochemical and molecular biological studies of serous cystadenoma of the pancreas. Pancreas 1998; 16: 40-4.
