Posterior Reversible Encephalopathy Syndrome in children/ adolescents with hematologic malignancies: Case reports
DOI:
https://doi.org/10.62438/tunismed.v103i4.5069Keywords:
case report, chemotherapy, children, hematologic diseases, posterior leukoencephalopathy syndromeAbstract
Introduction: Posterior Reversible Encephalopathy Syndrome (PRES) is one of the most common neurological complications in pediatric onco-hematology. Hematologic malignancies and cytotoxic chemotherapy are involved in its pathogenesis. It’s a clinical and radiological entity: the diagnosis of PRES is based on both clinical symptoms and neuroimaging data.
Observation: Here we reported a series of four cases of children/ adolescents treated by cytotoxic chemotherapy for hematologic malignancies who developed neurologic disorders and their magnetic resonance imaging findings were in favor of PRES.
Conclusion:In onco-hematology, children/ adolescents who present with new seizures, visual deficits, or other neurologic signs, PRES should be considered as a part of the differential diagnosis as a good outcome relies on rapid management of this complication
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